Sunday, December 6, 2009

Treatment of Colitis


Standard ulcerative colitis treatment depends on extent of involvement and disease severity. The goal is to induce remission initially with medications, followed by the administration of maintenance medications to prevent a relapse of the disease. The concept of induction of remission and maintenance of remission is very important. The medications used to induce and maintain a remission somewhat overlap, but the treatments are different. Physicians first direct treatment to inducing a remission which involves relief of symptoms and mucosal healing of the lining of the colon and then longer term treatment to maintain the remission.

Drugs used

Aminosalicylates
Mesalazine, also known as 5-aminosalicylic acid, 5-ASA, Asacol, Pentasa and Mesalamine.
Sulfasalazine, also known as Azulfidine.
Balsalazide, also known as Colazal.
Olsalazine, also known as Dipentum.
Corticosteroids
Cortisone
Prednisone
Prednisolone
Hydrocortisone
Methylprednisolone
Budesonide
Immunosuppressive drugs
Mercaptopurine, also known as 6-Mercaptopurine, 6-MP and Purinethiol.
Azathioprine, also known as Imuran (US) or Azasan, which metabolises to 6-MP.
Methotrexate, which inhibits folic acid
Biological treatment
Infliximab

Alternative Treatments

Aloe Mucilaginous Polysaccharides

Aloe mucilaginous polysaccharides are long-chain sugar molecules composed of individual mannose and glucose sugar molecules connected together — which have been attributed to subduing and reducing symptoms associated with ulcerative colitis.
We recommend SEROVERA® AMP 500. SEROVERA® AMP 500 is a GI-specific supplement that has been used with great success by individuals with UC.

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